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Sucralfate Brand names, Sucralfate Analogs

Sucralfate Brand Names Mixture

  • No information avaliable

Sucralfate Chemical_Formula


Sucralfate RX_link

Sucralfate fda sheet

Sucralfate msds (material safety sheet)

Sucralfate MSDS

Sucralfate Synthesis Reference

No information avaliable

Sucralfate Molecular Weight

1599.14 g/mol

Sucralfate Melting Point

No information avaliable

Sucralfate H2O Solubility

Insoluble in cold water

Sucralfate State


Sucralfate LogP

No information avaliable

Sucralfate Dosage Forms

Suspension; Tablet for oral administration (1g)

Sucralfate Indication

For the short-term treatment (up to 8 weeks) of active duodenal ulcer. Also used as maintenance therapy for duodenal ulcer patients at reduced dosage (1 gram twice a day) after healing of acute ulcers.

Sucralfate Pharmacology

Sucralfate is a prescription medication used to treat peptic ulcers. The current clinical uses of sucralfate are limited. It is effective for the healing of duodenal ulcers, but it is not frequently used for this since more effective drugs (e.g. proton pump inhibitors) have been developed. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. Chemically, sucralfate is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. In acidic solutions (e.g. gastric acid) it forms a thick paste that has a strong negative charge.

Sucralfate Absorption

Minimally absorbed from the gastrointestinal tract (up to 5% of the disaccharide component and less than 0.02% of aluminum).

Sucralfate side effects and Toxicity

Acute oral toxicity (LD50) in mice is >8000 mg/kg. There is limited experience in humans with overdosage of sucralfate. Sucralfate is only minimally absorbed from the gastrointestinal tract and thus risks associated with acute overdosage should be minimal. In rare reports describing sucralfate overdose, most patients remained asymptomatic.

Sucralfate Patient Information

Sucralfate Organisms Affected

Humans and other mammals