Sotalol HCL
Sotalol HCL Brand names, Sotalol HCL Analogs
Sotalol HCL Brand Names Mixture
- No information avaliable
Sotalol HCL Chemical_Formula
C11H87Al9O55S8
Sotalol HCL RX_link
http://www.rxlist.com/cgi/generic/sucral.htm
Sotalol HCL fda sheet
Sotalol HCL msds (material safety sheet)
Sotalol HCL Synthesis Reference
No information avaliable
Sotalol HCL Molecular Weight
1599.14 g/mol
Sotalol HCL Melting Point
No information avaliable
Sotalol HCL H2O Solubility
Insoluble in cold water
Sotalol HCL State
Solid
Sotalol HCL LogP
No information avaliable
Sotalol HCL Dosage Forms
Suspension; Tablet for oral administration (1g)
Sotalol HCL Indication
For the short-term treatment (up to 8 weeks) of active duodenal ulcer. Also used as maintenance therapy for duodenal ulcer patients at reduced dosage (1 gram twice a day) after healing of acute ulcers.
Sotalol HCL Pharmacology
Sucralfate is a prescription medication used to treat peptic ulcers. The current clinical uses of sucralfate are limited. It is effective for the healing of duodenal ulcers, but it is not frequently used for this since more effective drugs (e.g. proton pump inhibitors) have been developed. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. Chemically, sucralfate is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. In acidic solutions (e.g. gastric acid) it forms a thick paste that has a strong negative charge.
Sotalol HCL Absorption
Minimally absorbed from the gastrointestinal tract (up to 5% of the disaccharide component and less than 0.02% of aluminum).
Sotalol HCL side effects and Toxicity
Acute oral toxicity (LD50) in mice is >8000 mg/kg. There is limited experience in humans with overdosage of sucralfate. Sucralfate is only minimally absorbed from the gastrointestinal tract and thus risks associated with acute overdosage should be minimal. In rare reports describing sucralfate overdose, most patients remained asymptomatic.
Sotalol HCL Patient Information
Sotalol HCL Organisms Affected
Humans and other mammals
