PharmacyCodes



Sorine en es it fr

Sorine Brand names, Sorine Analogs

Sorine Brand Names Mixture

  • No information avaliable

Sorine Chemical_Formula

C11H87Al9O55S8

Sorine RX_link

http://www.rxlist.com/cgi/generic/sucral.htm

Sorine fda sheet

Sorine msds (material safety sheet)

Sorine MSDS

Sorine Synthesis Reference

No information avaliable

Sorine Molecular Weight

1599.14 g/mol

Sorine Melting Point

No information avaliable

Sorine H2O Solubility

Insoluble in cold water

Sorine State

Solid

Sorine LogP

No information avaliable

Sorine Dosage Forms

Suspension; Tablet for oral administration (1g)

Sorine Indication

For the short-term treatment (up to 8 weeks) of active duodenal ulcer. Also used as maintenance therapy for duodenal ulcer patients at reduced dosage (1 gram twice a day) after healing of acute ulcers.

Sorine Pharmacology

Sucralfate is a prescription medication used to treat peptic ulcers. The current clinical uses of sucralfate are limited. It is effective for the healing of duodenal ulcers, but it is not frequently used for this since more effective drugs (e.g. proton pump inhibitors) have been developed. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. Chemically, sucralfate is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. In acidic solutions (e.g. gastric acid) it forms a thick paste that has a strong negative charge.

Sorine Absorption

Minimally absorbed from the gastrointestinal tract (up to 5% of the disaccharide component and less than 0.02% of aluminum).

Sorine side effects and Toxicity

Acute oral toxicity (LD50) in mice is >8000 mg/kg. There is limited experience in humans with overdosage of sucralfate. Sucralfate is only minimally absorbed from the gastrointestinal tract and thus risks associated with acute overdosage should be minimal. In rare reports describing sucralfate overdose, most patients remained asymptomatic.

Sorine Patient Information

Sorine Organisms Affected

Humans and other mammals