Betapace AF
Betapace AF Brand names, Betapace AF Analogs
Betapace AF Brand Names Mixture
- No information avaliable
Betapace AF Chemical_Formula
C11H87Al9O55S8
Betapace AF RX_link
http://www.rxlist.com/cgi/generic/sucral.htm
Betapace AF fda sheet
Betapace AF msds (material safety sheet)
Betapace AF Synthesis Reference
No information avaliable
Betapace AF Molecular Weight
1599.14 g/mol
Betapace AF Melting Point
No information avaliable
Betapace AF H2O Solubility
Insoluble in cold water
Betapace AF State
Solid
Betapace AF LogP
No information avaliable
Betapace AF Dosage Forms
Suspension; Tablet for oral administration (1g)
Betapace AF Indication
For the short-term treatment (up to 8 weeks) of active duodenal ulcer. Also used as maintenance therapy for duodenal ulcer patients at reduced dosage (1 gram twice a day) after healing of acute ulcers.
Betapace AF Pharmacology
Sucralfate is a prescription medication used to treat peptic ulcers. The current clinical uses of sucralfate are limited. It is effective for the healing of duodenal ulcers, but it is not frequently used for this since more effective drugs (e.g. proton pump inhibitors) have been developed. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. Chemically, sucralfate is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. In acidic solutions (e.g. gastric acid) it forms a thick paste that has a strong negative charge.
Betapace AF Absorption
Minimally absorbed from the gastrointestinal tract (up to 5% of the disaccharide component and less than 0.02% of aluminum).
Betapace AF side effects and Toxicity
Acute oral toxicity (LD50) in mice is >8000 mg/kg. There is limited experience in humans with overdosage of sucralfate. Sucralfate is only minimally absorbed from the gastrointestinal tract and thus risks associated with acute overdosage should be minimal. In rare reports describing sucralfate overdose, most patients remained asymptomatic.
Betapace AF Patient Information
Betapace AF Organisms Affected
Humans and other mammals
