Starsis
Brand names,
Starsis
Analogs
Starsis
Brand Names Mixture
Starsis
Chemical_Formula
C19H27NO3
Starsis
RX_link
http://www.rxlist.com/cgi/generic2/nateglinide.htm
Starsis
fda sheet
Starsis
msds (material safety sheet)
Starsis
Synthesis Reference
No information avaliable
Starsis
Molecular Weight
317.423 g/mol
Starsis
Melting Point
No information avaliable
Starsis
H2O Solubility
Practically insoluble
Starsis
State
Solid
Starsis
LogP
3.824
Starsis
Dosage Forms
Tablets (60, 120 mg)
Starsis
Indication
For use as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other anti-diabetic agents. Also indicated for use in combination with metformin.
Starsis
Pharmacology
Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets.
Starsis
Absorption
Rapidly absorbed following oral administration prior to a meal, absolute bioavailability is estimated to be approximately 73%.
Starsis
side effects and Toxicity
An overdose may result in an exaggerated glucose-lowering effect with the development of hypoglycemic symptoms.
Starsis
Patient Information
Starsis
Organisms Affected
Humans and other mammals