Starlix
Brand names,
Starlix
Analogs
Starlix
Brand Names Mixture
Starlix
Chemical_Formula
C19H27NO3
Starlix
RX_link
http://www.rxlist.com/cgi/generic2/nateglinide.htm
Starlix
fda sheet
Starlix
msds (material safety sheet)
Starlix
Synthesis Reference
No information avaliable
Starlix
Molecular Weight
317.423 g/mol
Starlix
Melting Point
No information avaliable
Starlix
H2O Solubility
Practically insoluble
Starlix
State
Solid
Starlix
LogP
3.824
Starlix
Dosage Forms
Tablets (60, 120 mg)
Starlix
Indication
For use as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other anti-diabetic agents. Also indicated for use in combination with metformin.
Starlix
Pharmacology
Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets.
Starlix
Absorption
Rapidly absorbed following oral administration prior to a meal, absolute bioavailability is estimated to be approximately 73%.
Starlix
side effects and Toxicity
An overdose may result in an exaggerated glucose-lowering effect with the development of hypoglycemic symptoms.
Starlix
Patient Information
Starlix
Organisms Affected
Humans and other mammals