Fastic
Brand names,
Fastic
Analogs
Fastic
Brand Names Mixture
Fastic
Chemical_Formula
C19H27NO3
Fastic
RX_link
http://www.rxlist.com/cgi/generic2/nateglinide.htm
Fastic
fda sheet
Fastic
msds (material safety sheet)
Fastic
Synthesis Reference
No information avaliable
Fastic
Molecular Weight
317.423 g/mol
Fastic
Melting Point
No information avaliable
Fastic
H2O Solubility
Practically insoluble
Fastic
State
Solid
Fastic
LogP
3.824
Fastic
Dosage Forms
Tablets (60, 120 mg)
Fastic
Indication
For use as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other anti-diabetic agents. Also indicated for use in combination with metformin.
Fastic
Pharmacology
Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets.
Fastic
Absorption
Rapidly absorbed following oral administration prior to a meal, absolute bioavailability is estimated to be approximately 73%.
Fastic
side effects and Toxicity
An overdose may result in an exaggerated glucose-lowering effect with the development of hypoglycemic symptoms.
Fastic
Patient Information
Fastic
Organisms Affected
Humans and other mammals