SDZ-DJN 608
Brand names,
SDZ-DJN 608
Analogs
SDZ-DJN 608
Brand Names Mixture
SDZ-DJN 608
Chemical_Formula
C19H27NO3
SDZ-DJN 608
RX_link
http://www.rxlist.com/cgi/generic2/nateglinide.htm
SDZ-DJN 608
fda sheet
SDZ-DJN 608
msds (material safety sheet)
SDZ-DJN 608
Synthesis Reference
No information avaliable
SDZ-DJN 608
Molecular Weight
317.423 g/mol
SDZ-DJN 608
Melting Point
No information avaliable
SDZ-DJN 608
H2O Solubility
Practically insoluble
SDZ-DJN 608
State
Solid
SDZ-DJN 608
LogP
3.824
SDZ-DJN 608
Dosage Forms
Tablets (60, 120 mg)
SDZ-DJN 608
Indication
For use as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other anti-diabetic agents. Also indicated for use in combination with metformin.
SDZ-DJN 608
Pharmacology
Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets.
SDZ-DJN 608
Absorption
Rapidly absorbed following oral administration prior to a meal, absolute bioavailability is estimated to be approximately 73%.
SDZ-DJN 608
side effects and Toxicity
An overdose may result in an exaggerated glucose-lowering effect with the development of hypoglycemic symptoms.
SDZ-DJN 608
Patient Information
SDZ-DJN 608
Organisms Affected
Humans and other mammals