Skelaxin
Brand names,
Skelaxin
Analogs
Skelaxin
Brand Names Mixture
Skelaxin
Chemical_Formula
C12H15NO3
Skelaxin
RX_link
http://www.rxlist.com/cgi/generic/metax.htm
Skelaxin
fda sheet
Skelaxin
msds (material safety sheet)
Skelaxin
Synthesis Reference
No information avaliable
Skelaxin
Molecular Weight
221.252 g/mol
Skelaxin
Melting Point
122 oC
Skelaxin
H2O Solubility
No information avaliable
Skelaxin
State
Solid
Skelaxin
LogP
1.603
Skelaxin
Dosage Forms
Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)
Skelaxin
Indication
For the treatment of painful musculoskeletal conditions
Skelaxin
Pharmacology
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.
Skelaxin
Absorption
The absolute bioavailability of metaxalone from Skelaxin tablets is not known.
Skelaxin
side effects and Toxicity
LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.
Skelaxin
Patient Information
Patient Information:
Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.
If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.
Skelaxin
Organisms Affected
Humans and other mammals