Methaxalonum

Methaxalonum Brand names, Methaxalonum Analogs

Methaxalonum Brand Names Mixture

No information avaliable

Methaxalonum Chemical_Formula

C₁₂H₁₅NO₃

Methaxalonum RX_link

http://www.rxlist.com/cgi/generic/metax.htm

Methaxalonum fda sheet

Methaxalonum FDA

Methaxalonum msds (material safety sheet)

Methaxalonum Synthesis Reference

No information avaliable

Methaxalonum Molecular Weight

221.252 g/mol

Methaxalonum Melting Point

122 ^oC

Methaxalonum H₂O Solubility

No information avaliable

Methaxalonum State

Solid

Methaxalonum LogP

1.603

Methaxalonum Dosage Forms

Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)

Methaxalonum Indication

For the treatment of painful musculoskeletal conditions

Methaxalonum Pharmacology

Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.

Methaxalonum Absorption

The absolute bioavailability of metaxalone from Skelaxin tablets is not known.

Methaxalonum side effects and Toxicity

LD₅₀=775mg/kg (Rat, oral); LD₅₀=1690 mg/kg (Mouse, oral). When determining the LD₅₀ in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD₅₀ could be determined as the higher doses produced an emetic action in 15 to 30 minutes.

Methaxalonum Patient Information

Patient Information:

Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.

If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.

Methaxalonum Organisms Affected

Humans and other mammals