PharmacyCodes



Metazolone en es it fr

Metazolone Brand names, Metazolone Analogs

Metazolone Brand Names Mixture

  • No information avaliable

Metazolone Chemical_Formula

C12H15NO3

Metazolone RX_link

http://www.rxlist.com/cgi/generic/metax.htm

Metazolone fda sheet

Metazolone FDA

Metazolone msds (material safety sheet)

Metazolone Synthesis Reference

No information avaliable

Metazolone Molecular Weight

221.252 g/mol

Metazolone Melting Point

122 oC

Metazolone H2O Solubility

No information avaliable

Metazolone State

Solid

Metazolone LogP

1.603

Metazolone Dosage Forms

Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)

Metazolone Indication

For the treatment of painful musculoskeletal conditions

Metazolone Pharmacology

Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.

Metazolone Absorption

The absolute bioavailability of metaxalone from Skelaxin tablets is not known.

Metazolone side effects and Toxicity

LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.

Metazolone Patient Information

Patient Information:

Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.

If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.

Metazolone Organisms Affected

Humans and other mammals