Scopolamine
Brand names,
Scopolamine
Analogs
Scopolamine
Brand Names Mixture
Scopolamine
Chemical_Formula
C17H21NO4
Scopolamine
RX_link
No information avaliable
Scopolamine
fda sheet
Scopolamine
msds (material safety sheet)
Scopolamine
Synthesis Reference
No information avaliable
Scopolamine
Molecular Weight
303.353 g/mol
Scopolamine
Melting Point
No information avaliable
Scopolamine
H2O Solubility
No information avaliable
Scopolamine
State
Solid
Scopolamine
LogP
1.659
Scopolamine
Dosage Forms
Liquid
Scopolamine
Indication
For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness.
Scopolamine
Pharmacology
Scopolamine is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Scopolamine has many uses including the prevention of motion sickness. It is not clear how Scopolamine prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that Scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Scopolamine also may work directly on the vomiting center. Scopolamine must be taken before the onset of motion sickness to be effective.
Scopolamine
Absorption
No information avaliable
Scopolamine
side effects and Toxicity
No information avaliable
Scopolamine
Patient Information
No information avaliable
Scopolamine
Organisms Affected
Humans and other mammals