Skopolamin
Brand names,
Skopolamin
Analogs
Skopolamin
Brand Names Mixture
Skopolamin
Chemical_Formula
C17H21NO4
Skopolamin
RX_link
No information avaliable
Skopolamin
fda sheet
Skopolamin
msds (material safety sheet)
Skopolamin
Synthesis Reference
No information avaliable
Skopolamin
Molecular Weight
303.353 g/mol
Skopolamin
Melting Point
No information avaliable
Skopolamin
H2O Solubility
No information avaliable
Skopolamin
State
Solid
Skopolamin
LogP
1.659
Skopolamin
Dosage Forms
Liquid
Skopolamin
Indication
For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness.
Skopolamin
Pharmacology
Scopolamine is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Scopolamine has many uses including the prevention of motion sickness. It is not clear how Scopolamine prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that Scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Scopolamine also may work directly on the vomiting center. Scopolamine must be taken before the onset of motion sickness to be effective.
Skopolamin
Absorption
No information avaliable
Skopolamin
side effects and Toxicity
No information avaliable
Skopolamin
Patient Information
No information avaliable
Skopolamin
Organisms Affected
Humans and other mammals