Ranolazine Dihydrochloride
Brand names,
Ranolazine Dihydrochloride
Analogs
Ranolazine Dihydrochloride
Brand Names Mixture
Ranolazine Dihydrochloride
Chemical_Formula
C41H76N2O15
Ranolazine Dihydrochloride
RX_link
No information avaliable
Ranolazine Dihydrochloride
fda sheet
Ranolazine Dihydrochloride
msds (material safety sheet)
Ranolazine Dihydrochloride
Synthesis Reference
No information avaliable
Ranolazine Dihydrochloride
Molecular Weight
837.047 g/mol
Ranolazine Dihydrochloride
Melting Point
No information avaliable
Ranolazine Dihydrochloride
H2O Solubility
0.0189 mg/L at 25 oC (SRC PhysProp estimated -- MEYLAN,WM et al. (1996))
Ranolazine Dihydrochloride
State
Solid
Ranolazine Dihydrochloride
LogP
2.292
Ranolazine Dihydrochloride
Dosage Forms
Tablets; Oral suspension
Ranolazine Dihydrochloride
Indication
Used to treat respiratory tract, urinary and soft tissue infections.
Ranolazine Dihydrochloride
Pharmacology
Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi. Roxithromycin is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxithromycin enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxithromycin also possesses intracellular bactericidal activity.
Ranolazine Dihydrochloride
Absorption
Very rapidly absorbed and diffused into most tissues and phagocytes.
Ranolazine Dihydrochloride
side effects and Toxicity
Most common side-effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting. Less common side-effects include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.
Ranolazine Dihydrochloride
Patient Information
Ranolazine Dihydrochloride
Organisms Affected
Enteric bacteria and other eubacteria