Ranexa
Ranexa Brand names, Ranexa Analogs
Ranexa Brand Names Mixture
- No information avaliable
Ranexa Chemical_Formula
C41H76N2O15
Ranexa RX_link
No information avaliable
Ranexa fda sheet
Ranexa msds (material safety sheet)
Ranexa Synthesis Reference
No information avaliable
Ranexa Molecular Weight
837.047 g/mol
Ranexa Melting Point
No information avaliable
Ranexa H2O Solubility
0.0189 mg/L at 25 oC (SRC PhysProp estimated -- MEYLAN,WM et al. (1996))
Ranexa State
Solid
Ranexa LogP
2.292
Ranexa Dosage Forms
Tablets; Oral suspension
Ranexa Indication
Used to treat respiratory tract, urinary and soft tissue infections.
Ranexa Pharmacology
Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi. Roxithromycin is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxithromycin enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxithromycin also possesses intracellular bactericidal activity.
Ranexa Absorption
Very rapidly absorbed and diffused into most tissues and phagocytes.
Ranexa side effects and Toxicity
Most common side-effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting. Less common side-effects include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.
Ranexa Patient Information
Ranexa Organisms Affected
Enteric bacteria and other eubacteria
