Ranolazine 2HCl
Brand names,
Ranolazine 2HCl
Analogs
Ranolazine 2HCl
Brand Names Mixture
Ranolazine 2HCl
Chemical_Formula
C41H76N2O15
Ranolazine 2HCl
RX_link
No information avaliable
Ranolazine 2HCl
fda sheet
Ranolazine 2HCl
msds (material safety sheet)
Ranolazine 2HCl
Synthesis Reference
No information avaliable
Ranolazine 2HCl
Molecular Weight
837.047 g/mol
Ranolazine 2HCl
Melting Point
No information avaliable
Ranolazine 2HCl
H2O Solubility
0.0189 mg/L at 25 oC (SRC PhysProp estimated -- MEYLAN,WM et al. (1996))
Ranolazine 2HCl
State
Solid
Ranolazine 2HCl
LogP
2.292
Ranolazine 2HCl
Dosage Forms
Tablets; Oral suspension
Ranolazine 2HCl
Indication
Used to treat respiratory tract, urinary and soft tissue infections.
Ranolazine 2HCl
Pharmacology
Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi. Roxithromycin is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxithromycin enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxithromycin also possesses intracellular bactericidal activity.
Ranolazine 2HCl
Absorption
Very rapidly absorbed and diffused into most tissues and phagocytes.
Ranolazine 2HCl
side effects and Toxicity
Most common side-effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting. Less common side-effects include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.
Ranolazine 2HCl
Patient Information
Ranolazine 2HCl
Organisms Affected
Enteric bacteria and other eubacteria