Pulmozyme (Genentech Inc)
Brand names,
Pulmozyme (Genentech Inc)
Analogs
Pulmozyme (Genentech Inc)
Brand Names Mixture
Pulmozyme (Genentech Inc)
Chemical_Formula
C1321H1999N339O396S9
Pulmozyme (Genentech Inc)
RX_link
http://www.rxlist.com/cgi/generic3/pulmozyme.htm
Pulmozyme (Genentech Inc)
fda sheet
Pulmozyme (Genentech Inc)
msds (material safety sheet)
Pulmozyme (Genentech Inc)
Synthesis Reference
No information avaliable
Pulmozyme (Genentech Inc)
Molecular Weight
29253.9
Pulmozyme (Genentech Inc)
Melting Point
67 oC (Chan, H.K. et al., Pharm Res. 13:756-761 (1996))
Pulmozyme (Genentech Inc)
H2O Solubility
No information avaliable
Pulmozyme (Genentech Inc)
State
Liquid
Pulmozyme (Genentech Inc)
LogP
-0.083
Pulmozyme (Genentech Inc)
Dosage Forms
Solution
Pulmozyme (Genentech Inc)
Indication
For treatment of cystic fibrosis
Pulmozyme (Genentech Inc)
Pharmacology
Cystic fibrosis (CF) is a disease characterized by the retention of viscous purulent secretions in the airways. These thick secretions contribute both to reduced pulmonary function and to frequent pulmonary infection. Purulent pulmonary secretions contain very high concentrations of extracellular DNA released by degenerating leukocytes that accumulate in response to these infections. Pulmozyme hydrolyzes the DNA in sputum of CF patients and reduces sputum viscoelasticity.
Pulmozyme (Genentech Inc)
Absorption
No information avaliable
Pulmozyme (Genentech Inc)
side effects and Toxicity
No information avaliable
Pulmozyme (Genentech Inc)
Patient Information
BIOD00001.html
Pulmozyme (Genentech Inc)
Organisms Affected
Humans and other mammals