PharmacyCodes



DNase I en es it fr

DNase I Brand names, DNase I Analogs

DNase I Brand Names Mixture

  • No information avaliable

DNase I Chemical_Formula

C1321H1999N339O396S9

DNase I RX_link

http://www.rxlist.com/cgi/generic3/pulmozyme.htm

DNase I fda sheet

DNase I msds (material safety sheet)

DNase I Synthesis Reference

No information avaliable

DNase I Molecular Weight

29253.9

DNase I Melting Point

67 oC (Chan, H.K. et al., Pharm Res. 13:756-761 (1996))

DNase I H2O Solubility

No information avaliable

DNase I State

Liquid

DNase I LogP

-0.083

DNase I Dosage Forms

Solution

DNase I Indication

For treatment of cystic fibrosis

DNase I Pharmacology

Cystic fibrosis (CF) is a disease characterized by the retention of viscous purulent secretions in the airways. These thick secretions contribute both to reduced pulmonary function and to frequent pulmonary infection. Purulent pulmonary secretions contain very high concentrations of extracellular DNA released by degenerating leukocytes that accumulate in response to these infections. Pulmozyme hydrolyzes the DNA in sputum of CF patients and reduces sputum viscoelasticity.

DNase I Absorption

No information avaliable

DNase I side effects and Toxicity

No information avaliable

DNase I Patient Information

BIOD00001.html

DNase I Organisms Affected

Humans and other mammals