Deoxyribonuclease I
Deoxyribonuclease I Brand names, Deoxyribonuclease I Analogs
Deoxyribonuclease I Brand Names Mixture
- No information avaliable
Deoxyribonuclease I Chemical_Formula
C1321H1999N339O396S9
Deoxyribonuclease I RX_link
http://www.rxlist.com/cgi/generic3/pulmozyme.htm
Deoxyribonuclease I fda sheet
Deoxyribonuclease I msds (material safety sheet)
Deoxyribonuclease I Synthesis Reference
No information avaliable
Deoxyribonuclease I Molecular Weight
29253.9
Deoxyribonuclease I Melting Point
67 oC (Chan, H.K. et al., Pharm Res. 13:756-761 (1996))
Deoxyribonuclease I H2O Solubility
No information avaliable
Deoxyribonuclease I State
Liquid
Deoxyribonuclease I LogP
-0.083
Deoxyribonuclease I Dosage Forms
Solution
Deoxyribonuclease I Indication
For treatment of cystic fibrosis
Deoxyribonuclease I Pharmacology
Cystic fibrosis (CF) is a disease characterized by the retention of viscous purulent secretions in the airways. These thick secretions contribute both to reduced pulmonary function and to frequent pulmonary infection. Purulent pulmonary secretions contain very high concentrations of extracellular DNA released by degenerating leukocytes that accumulate in response to these infections. Pulmozyme hydrolyzes the DNA in sputum of CF patients and reduces sputum viscoelasticity.
Deoxyribonuclease I Absorption
No information avaliable
Deoxyribonuclease I side effects and Toxicity
No information avaliable
Deoxyribonuclease I Patient Information
BIOD00001.html
Deoxyribonuclease I Organisms Affected
Humans and other mammals
