Plavix
Plavix Brand names, Plavix Analogs
Plavix Brand Names Mixture
- No information avaliable
Plavix Chemical_Formula
C16H16ClNO2S
Plavix RX_link
http://www.rxlist.com/cgi/generic/clopidog.htm
Plavix fda sheet
Plavix msds (material safety sheet)
Plavix Synthesis Reference
D. Aubert et al.; U.S. Pat. 4,529,596(1985)
Plavix Molecular Weight
321.822 g/mol
Plavix Melting Point
158oC
Plavix H2O Solubility
50.78 mg/L
Plavix State
solid
Plavix LogP
No information avaliable
Plavix Dosage Forms
Tablet (round, biconvex, film-coated)
Plavix Indication
For the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by recent stroke, recent myocardial infarction, or established peripheral arterial disease
Plavix Pharmacology
Clopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to reduce atherosclerotic events such as myocardial infarction, stroke, and vascular death in patients who have had a recent stroke, recent MI, or have established peripheral vascular disease.
Plavix Absorption
Absorption is at least 50% based on urinary excretion of clopidogrel-related metabolites. Bioavailability has not been found to be affected by food.
Plavix side effects and Toxicity
Symptoms of acute toxicity include vomiting (in baboons), prostration, difficult breathing, and gastrointestinal hemorrhage.
Plavix Patient Information
Patients should be told that they may bleed more easily and it may take them longer than usual to stop bleeding when they take Plavix or Plavix combined with aspirin, and that they should report any unusual bleeding to their physician. Patients should inform physicians and dentists that they are taking Plavix and/or any other product known to affect bleeding before any surgery is scheduled and before any new drug is taken.
Plavix Organisms Affected
Humans and other mammals
