Pioglitazone Hydrochloride
Pioglitazone Hydrochloride Brand names, Pioglitazone Hydrochloride Analogs
Pioglitazone Hydrochloride Brand Names Mixture
- No information avaliable
Pioglitazone Hydrochloride Chemical_Formula
C19H20N2O3S
Pioglitazone Hydrochloride RX_link
http://www.rxlist.com/cgi/generic2/pioglit.htm
Pioglitazone Hydrochloride fda sheet
Pioglitazone Hydrochloride msds (material safety sheet)
Pioglitazone Hydrochloride Synthesis Reference
K. Meguro, T. Fujita, U.S. Pat. 4,687,777 (1987)
Pioglitazone Hydrochloride Molecular Weight
356.44 g/mol
Pioglitazone Hydrochloride Melting Point
183-184oC
Pioglitazone Hydrochloride H2O Solubility
mg/mL
Pioglitazone Hydrochloride State
Solid
Pioglitazone Hydrochloride LogP
No information avaliable
Pioglitazone Hydrochloride Dosage Forms
Oral tablets
Pioglitazone Hydrochloride Indication
Treatment of Type II diabetes mellitus
Pioglitazone Hydrochloride Pharmacology
Pioglitazone, a member of the drug group known as the thiazolidinediones or "insulin sensitizers", is not chemically or functionally related to the alpha-glucosidase inhibitors, the biguanides, or the sulfonylureas. Pioglitazone targets insulin resistance and, hence, is used alone or in combination with insulin, metformin, or asulfonylurea as an antidiabetic agent.
Pioglitazone Hydrochloride Absorption
Following oral administration, in the fasting state, pioglitazone is first measurable in serum within 30 minutes, with peak concentrations observed within 2 hours. Food slightly delays the time to peak serum concentration to 3 to 4 hours, but does not alter the extent of absorption.
Pioglitazone Hydrochloride side effects and Toxicity
Hypogycemia; LD50=mg/kg (orally in rat)
Pioglitazone Hydrochloride Patient Information
Pioglitazone Hydrochloride Organisms Affected
Humans and other mammals
