Actos
Actos Brand names, Actos Analogs
Actos Brand Names Mixture
- No information avaliable
Actos Chemical_Formula
C19H20N2O3S
Actos RX_link
http://www.rxlist.com/cgi/generic2/pioglit.htm
Actos fda sheet
Actos msds (material safety sheet)
Actos Synthesis Reference
K. Meguro, T. Fujita, U.S. Pat. 4,687,777 (1987)
Actos Molecular Weight
356.44 g/mol
Actos Melting Point
183-184oC
Actos H2O Solubility
mg/mL
Actos State
Solid
Actos LogP
No information avaliable
Actos Dosage Forms
Oral tablets
Actos Indication
Treatment of Type II diabetes mellitus
Actos Pharmacology
Pioglitazone, a member of the drug group known as the thiazolidinediones or "insulin sensitizers", is not chemically or functionally related to the alpha-glucosidase inhibitors, the biguanides, or the sulfonylureas. Pioglitazone targets insulin resistance and, hence, is used alone or in combination with insulin, metformin, or asulfonylurea as an antidiabetic agent.
Actos Absorption
Following oral administration, in the fasting state, pioglitazone is first measurable in serum within 30 minutes, with peak concentrations observed within 2 hours. Food slightly delays the time to peak serum concentration to 3 to 4 hours, but does not alter the extent of absorption.
Actos side effects and Toxicity
Hypogycemia; LD50=mg/kg (orally in rat)
Actos Patient Information
Actos Organisms Affected
Humans and other mammals
