PharmacyCodes



Pemirolast en es it fr

Pemirolast Brand names, Pemirolast Analogs

Pemirolast Brand Names Mixture

  • No information avaliable

Pemirolast Chemical_Formula

C10H8N6O

Pemirolast RX_link

http://www.rxlist.com/cgi/generic/alamast.htm

Pemirolast fda sheet

Pemirolast FDA

Pemirolast msds (material safety sheet)

Pemirolast Synthesis Reference

No information avaliable

Pemirolast Molecular Weight

228.21 g/mol

Pemirolast Melting Point

No information avaliable

Pemirolast H2O Solubility

No information avaliable

Pemirolast State

Solid

Pemirolast LogP

-0.192

Pemirolast Dosage Forms

Ophthalmic solution

Pemirolast Indication

For the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis

Pemirolast Pharmacology

Pemirolast is used for the prophylactic treatment of itching of the eye associated with allergic conjunctivitis. Pemirolast potassium is a mast cell stabilizer that inhibits the in vivo Type I immediate hypersensitivity reaction. Pemirolast inhibits the antigen-induced release of inflammatory mediators (e.g., histamine, leukotriene C4, D4, E4) from human mast cells. Allergic reactions lead to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, Pemirolast is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of blood vessels. It provides effective, temporary relief of watery and itchy eyes.

Pemirolast Absorption

No information avaliable

Pemirolast side effects and Toxicity

No information avaliable

Pemirolast Patient Information

To prevent contaminating the dropper tip and solution, do not touch the eyelids or surrounding areas with the dropper tip. Keep the bottle tightly closed when not in use.

Patients should be advised not to wear contact lenses if their eyes are red. ALAMAST should not be used to treat contact lens related irritation. The preservative in ALAMAST, lauralkonium chloride, may be absorbed by soft contact lenses. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALAMAST before they insert their contact lenses.

Pemirolast Organisms Affected

Humans and other mammals