PharmacyCodes



Pemirolastum [Inn-Latin] en es it fr

Pemirolastum [Inn-Latin] Brand names, Pemirolastum [Inn-Latin] Analogs

Pemirolastum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Pemirolastum [Inn-Latin] Chemical_Formula

C10H8N6O

Pemirolastum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/alamast.htm

Pemirolastum [Inn-Latin] fda sheet

Pemirolastum_[Inn-Latin] FDA

Pemirolastum [Inn-Latin] msds (material safety sheet)

Pemirolastum [Inn-Latin] Synthesis Reference

No information avaliable

Pemirolastum [Inn-Latin] Molecular Weight

228.21 g/mol

Pemirolastum [Inn-Latin] Melting Point

No information avaliable

Pemirolastum [Inn-Latin] H2O Solubility

No information avaliable

Pemirolastum [Inn-Latin] State

Solid

Pemirolastum [Inn-Latin] LogP

-0.192

Pemirolastum [Inn-Latin] Dosage Forms

Ophthalmic solution

Pemirolastum [Inn-Latin] Indication

For the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis

Pemirolastum [Inn-Latin] Pharmacology

Pemirolast is used for the prophylactic treatment of itching of the eye associated with allergic conjunctivitis. Pemirolast potassium is a mast cell stabilizer that inhibits the in vivo Type I immediate hypersensitivity reaction. Pemirolast inhibits the antigen-induced release of inflammatory mediators (e.g., histamine, leukotriene C4, D4, E4) from human mast cells. Allergic reactions lead to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, Pemirolast is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of blood vessels. It provides effective, temporary relief of watery and itchy eyes.

Pemirolastum [Inn-Latin] Absorption

No information avaliable

Pemirolastum [Inn-Latin] side effects and Toxicity

No information avaliable

Pemirolastum [Inn-Latin] Patient Information

To prevent contaminating the dropper tip and solution, do not touch the eyelids or surrounding areas with the dropper tip. Keep the bottle tightly closed when not in use.

Patients should be advised not to wear contact lenses if their eyes are red. ALAMAST should not be used to treat contact lens related irritation. The preservative in ALAMAST, lauralkonium chloride, may be absorbed by soft contact lenses. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALAMAST before they insert their contact lenses.

Pemirolastum [Inn-Latin] Organisms Affected

Humans and other mammals