Alamast
Alamast Brand names, Alamast Analogs
Alamast Brand Names Mixture
- No information avaliable
Alamast Chemical_Formula
C10H8N6O
Alamast RX_link
http://www.rxlist.com/cgi/generic/alamast.htm
Alamast fda sheet
Alamast msds (material safety sheet)
Alamast Synthesis Reference
No information avaliable
Alamast Molecular Weight
228.21 g/mol
Alamast Melting Point
No information avaliable
Alamast H2O Solubility
No information avaliable
Alamast State
Solid
Alamast LogP
-0.192
Alamast Dosage Forms
Ophthalmic solution
Alamast Indication
For the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis
Alamast Pharmacology
Pemirolast is used for the prophylactic treatment of itching of the eye associated with allergic conjunctivitis. Pemirolast potassium is a mast cell stabilizer that inhibits the in vivo Type I immediate hypersensitivity reaction. Pemirolast inhibits the antigen-induced release of inflammatory mediators (e.g., histamine, leukotriene C4, D4, E4) from human mast cells. Allergic reactions lead to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, Pemirolast is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of blood vessels. It provides effective, temporary relief of watery and itchy eyes.
Alamast Absorption
No information avaliable
Alamast side effects and Toxicity
No information avaliable
Alamast Patient Information
To prevent contaminating the dropper tip and solution, do not touch the eyelids or surrounding areas with the dropper tip. Keep the bottle tightly closed when not in use.
Patients should be advised not to wear contact lenses if their eyes are red. ALAMAST should not be used to treat contact lens related irritation. The preservative in ALAMAST, lauralkonium chloride, may be absorbed by soft contact lenses. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALAMAST before they insert their contact lenses.
Alamast Organisms Affected
Humans and other mammals
