Pegaspargase
Brand names,
Pegaspargase
Analogs
Pegaspargase
Brand Names Mixture
Pegaspargase
Chemical_Formula
C1377H2208N382O442S17
Pegaspargase
RX_link
http://www.rxlist.com/cgi/generic2/pegaspargase.htm
Pegaspargase
fda sheet
Pegaspargase
msds (material safety sheet)
Pegaspargase
Synthesis Reference
No information avaliable
Pegaspargase
Molecular Weight
31731.9
Pegaspargase
Melting Point
No information avaliable
Pegaspargase
H2O Solubility
No information avaliable
Pegaspargase
State
Liquid
Pegaspargase
LogP
0.059
Pegaspargase
Dosage Forms
Solution (IM or IV Administration)
Pegaspargase
Indication
For treatment of acute lymphoblastic leukemia
Pegaspargase
Pharmacology
In a significant number of patients with acute leukemia, the malignant cells are dependent on an exogenous source of asparagine for survival. Normal cells, however, are able to synthesize asparagine and thus are affected less by the rapid depletion produced by treatment with the enzyme asparaginase. Oncaspar exploits a metabolic defect in asparagine synthesis of some malignant cells.
Pegaspargase
Absorption
No information avaliable
Pegaspargase
side effects and Toxicity
No information avaliable
Pegaspargase
Patient Information
No information avaliable
Pegaspargase
Organisms Affected
Humans and other mammals