L-asparagine amidohydrolase
Brand names,
L-asparagine amidohydrolase
Analogs
L-asparagine amidohydrolase
Brand Names Mixture
L-asparagine amidohydrolase
Chemical_Formula
C1377H2208N382O442S17
L-asparagine amidohydrolase
RX_link
http://www.rxlist.com/cgi/generic3/asparaginase.htm
L-asparagine amidohydrolase
fda sheet
L-asparagine amidohydrolase
msds (material safety sheet)
L-asparagine amidohydrolase
Synthesis Reference
No information avaliable
L-asparagine amidohydrolase
Molecular Weight
31731.9
L-asparagine amidohydrolase
Melting Point
No information avaliable
L-asparagine amidohydrolase
H2O Solubility
No information avaliable
L-asparagine amidohydrolase
State
Liquid
L-asparagine amidohydrolase
LogP
0.059
L-asparagine amidohydrolase
Dosage Forms
Powder for solution; Solution (IV or IM injection)
L-asparagine amidohydrolase
Indication
For treatment of acute lympocytic leukemia and non-Hodgkins lymphoma
L-asparagine amidohydrolase
Pharmacology
In a significant number of patients with acute leukemia, the malignant cells are dependent on an exogenous source of asparagine for survival. Normal cells, however, are able to synthesize asparagine and thus are affected less by the rapid depletion produced by treatment with the enzyme asparaginase. Elspar exploits a metabolic defect in asparagine synthesis of some malignant cells.
L-asparagine amidohydrolase
Absorption
No information avaliable
L-asparagine amidohydrolase
side effects and Toxicity
No information avaliable
L-asparagine amidohydrolase
Patient Information
No information avaliable
L-asparagine amidohydrolase
Organisms Affected
Humans and other mammals