Oncaspar (Enzon Inc)
Brand names,
Oncaspar (Enzon Inc)
Analogs
Oncaspar (Enzon Inc)
Brand Names Mixture
Oncaspar (Enzon Inc)
Chemical_Formula
C1377H2208N382O442S17
Oncaspar (Enzon Inc)
RX_link
http://www.rxlist.com/cgi/generic2/pegaspargase.htm
Oncaspar (Enzon Inc)
fda sheet
Oncaspar (Enzon Inc)
msds (material safety sheet)
Oncaspar (Enzon Inc)
Synthesis Reference
No information avaliable
Oncaspar (Enzon Inc)
Molecular Weight
31731.9
Oncaspar (Enzon Inc)
Melting Point
No information avaliable
Oncaspar (Enzon Inc)
H2O Solubility
No information avaliable
Oncaspar (Enzon Inc)
State
Liquid
Oncaspar (Enzon Inc)
LogP
0.059
Oncaspar (Enzon Inc)
Dosage Forms
Solution (IM or IV Administration)
Oncaspar (Enzon Inc)
Indication
For treatment of acute lymphoblastic leukemia
Oncaspar (Enzon Inc)
Pharmacology
In a significant number of patients with acute leukemia, the malignant cells are dependent on an exogenous source of asparagine for survival. Normal cells, however, are able to synthesize asparagine and thus are affected less by the rapid depletion produced by treatment with the enzyme asparaginase. Oncaspar exploits a metabolic defect in asparagine synthesis of some malignant cells.
Oncaspar (Enzon Inc)
Absorption
No information avaliable
Oncaspar (Enzon Inc)
side effects and Toxicity
No information avaliable
Oncaspar (Enzon Inc)
Patient Information
No information avaliable
Oncaspar (Enzon Inc)
Organisms Affected
Humans and other mammals