Putative L-asparaginase precursor
Brand names,
Putative L-asparaginase precursor
Analogs
Putative L-asparaginase precursor
Brand Names Mixture
Putative L-asparaginase precursor
Chemical_Formula
C1377H2208N382O442S17
Putative L-asparaginase precursor
RX_link
http://www.rxlist.com/cgi/generic3/asparaginase.htm
Putative L-asparaginase precursor
fda sheet
Putative L-asparaginase precursor
msds (material safety sheet)
Putative L-asparaginase precursor
Synthesis Reference
No information avaliable
Putative L-asparaginase precursor
Molecular Weight
31731.9
Putative L-asparaginase precursor
Melting Point
No information avaliable
Putative L-asparaginase precursor
H2O Solubility
No information avaliable
Putative L-asparaginase precursor
State
Liquid
Putative L-asparaginase precursor
LogP
0.059
Putative L-asparaginase precursor
Dosage Forms
Powder for solution; Solution (IV or IM injection)
Putative L-asparaginase precursor
Indication
For treatment of acute lympocytic leukemia and non-Hodgkins lymphoma
Putative L-asparaginase precursor
Pharmacology
In a significant number of patients with acute leukemia, the malignant cells are dependent on an exogenous source of asparagine for survival. Normal cells, however, are able to synthesize asparagine and thus are affected less by the rapid depletion produced by treatment with the enzyme asparaginase. Elspar exploits a metabolic defect in asparagine synthesis of some malignant cells.
Putative L-asparaginase precursor
Absorption
No information avaliable
Putative L-asparaginase precursor
side effects and Toxicity
No information avaliable
Putative L-asparaginase precursor
Patient Information
No information avaliable
Putative L-asparaginase precursor
Organisms Affected
Humans and other mammals