Oxiconazole nitrate

• Antifibrinolytic Agents
• ATC:B02AA02

• Fungibacid
• GyneCure
• GyneCure Ovules
• GyneCure Vaginal Ointment Tandempak
• GyneCure Vaginal Ovules Tandempak
• Gyno-trosyd
• Monistat 1
• Oxiconazolc Nitrate
• Oxiconazole
• Oxiconazole nitrate
• Thioconazole
• Tioconazol [INN-Spanish]
• Tioconazole [USAN:BAN:INN:JAN]
• Tioconazolum [INN-Latin]
• Trosyd
• Trosyd AF
• Trosyd J
• Trosyl
• Tz-3
• Vagistat
• Vagistat-1
• Zoniden

• No information avaliable

C₈H₁₅NO₂

http://www.rxlist.com/cgi/generic3/cyclapron.htm

Oxiconazole_nitrate MSDS

No information avaliable

157.21 g/mol

>300 ^oC

1.67E+005 mg/L

Solid

0.66

Tablets containing 500 mg of tranexamic acid; Sterile solution for intravenous injection containing 100 mg tranexamic acid

For use in patients with hemophilia for short term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction.

Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin. Tranexamic acid is a competitive inhibitor of plasminogen activation, and at much higher concentrations, a noncompetitive inhibitor of plasmin, i.e., actions similar to aminocaproic acid. Tranexamic acid is about 10 times more potent in vitro than aminocaproic acid. Tranexamic acid binds more strongly than aminocaproic acid to both the strong and weak receptor sites of the plasminogen molecule in a ratio corresponding to the difference in potency between the compounds. Tranexamic acid in a concentration of 1 mg per mL does not aggregate platelets in vitro. In patients with hereditary angioedema, inhibition of the formation and activity of plasmin by tranexamic acid may prevent attacks of angioedema by decreasing plasmin-induced activation of the first complement protein (C1).

Absorption of tranexamic acid after oral administration in humans represents approximately 30 to 50% of the ingested dose and bioavailability is not affected by food intake.

Oral LD₅₀ in mice is >10 gm/kg. Symptoms of overdosage may be nausea, vomiting, orthostatic symptoms and/or hypotension.

Humans and other mammals