Olsalazine
Olsalazine Brand names, Olsalazine Analogs
Olsalazine Brand Names Mixture
- No information avaliable
Olsalazine Chemical_Formula
C17H19N3
Olsalazine RX_link
http://www.rxlist.com/cgi/generic/mirtaz.htm
Olsalazine fda sheet
Olsalazine msds (material safety sheet)
Olsalazine Synthesis Reference
W. J. Van der Burg, U.S. Pat. 4,062,848 (1977)
Olsalazine Molecular Weight
265.353 g/mol
Olsalazine Melting Point
114-116oC
Olsalazine H2O Solubility
Slight
Olsalazine State
Solid
Olsalazine LogP
2.369
Olsalazine Dosage Forms
Tablet; Tablet (orally disintegrating)
Olsalazine Indication
For the treatment of major depressive disorder.
Olsalazine Pharmacology
Mirtazapine, an antidepressant of the piperazinoazepine class, is a tetracyclic compound with an anxiolytic effect. Mirtazapine has fewer ADRs than tricyclic antidepressants and is better tolerated. Selective blockade of specific serotonin receptors by mirtazapine likey minimizes side effects typical of other antidepressants.
Olsalazine Absorption
Rapid and complete, but, due to first-pass metabolism, absolute bioavailability is 50%.
Olsalazine side effects and Toxicity
Symptoms of overdose include disorientation, drowsiness, impaired memory, and tachycardia. LD50=mg/kg (orally in rat).
Olsalazine Patient Information
Olsalazine Organisms Affected
Humans and other mammals
