Mirtazepine
Mirtazepine Brand names, Mirtazepine Analogs
Mirtazepine Brand Names Mixture
- No information avaliable
Mirtazepine Chemical_Formula
C17H19N3
Mirtazepine RX_link
http://www.rxlist.com/cgi/generic/mirtaz.htm
Mirtazepine fda sheet
Mirtazepine msds (material safety sheet)
Mirtazepine Synthesis Reference
W. J. Van der Burg, U.S. Pat. 4,062,848 (1977)
Mirtazepine Molecular Weight
265.353 g/mol
Mirtazepine Melting Point
114-116oC
Mirtazepine H2O Solubility
Slight
Mirtazepine State
Solid
Mirtazepine LogP
2.369
Mirtazepine Dosage Forms
Tablet; Tablet (orally disintegrating)
Mirtazepine Indication
For the treatment of major depressive disorder.
Mirtazepine Pharmacology
Mirtazapine, an antidepressant of the piperazinoazepine class, is a tetracyclic compound with an anxiolytic effect. Mirtazapine has fewer ADRs than tricyclic antidepressants and is better tolerated. Selective blockade of specific serotonin receptors by mirtazapine likey minimizes side effects typical of other antidepressants.
Mirtazepine Absorption
Rapid and complete, but, due to first-pass metabolism, absolute bioavailability is 50%.
Mirtazepine side effects and Toxicity
Symptoms of overdose include disorientation, drowsiness, impaired memory, and tachycardia. LD50=mg/kg (orally in rat).
Mirtazepine Patient Information
Mirtazepine Organisms Affected
Humans and other mammals
