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Nostel Brand names, Nostel Analogs

Nostel Brand Names Mixture

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Nostel Chemical_Formula


Nostel RX_link

Nostel fda sheet

Nostel FDA

Nostel msds (material safety sheet)

Nostel MSDS

Nostel Synthesis Reference

No information avaliable

Nostel Molecular Weight

206.028 g/mol

Nostel Melting Point

No information avaliable

Nostel H2O Solubility

No information avaliable

Nostel State


Nostel LogP


Nostel Dosage Forms

Solution for injection (50mg/mL); Tablet (200, 400 mg)

Nostel Indication

For the treatment of symptomatic Paget's disease of bone and in the prevention and treatment of heterotopic ossification following total hip replacement or due to spinal cord injury.

Nostel Pharmacology

Etidronate is a first generation (non-nitrogenous) bisphosphonate in the same family as clodronate and tiludronate. Etidronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the etidronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Etidronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Nostel Absorption

The amount of drug absorbed after an oral dose is approximately 3%.

Nostel side effects and Toxicity

Clinical experience with acute etidronate overdosage is extremely limited. Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients. Some patients may develop vomiting. In one event, an 18-year-old female who ingested an estimated single dose of 4800 to 6000 mg (67 to 100 mg/kg) of etidronate was reported to be mildly hypocalcemic (7 .5 2 mg/ dl) and experienced paresthesia of the fingers.

Nostel Patient Information

Nostel Organisms Affected

Humans and other mammals