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Arvynol Brand names, Arvynol Analogs

Arvynol Brand Names Mixture

  • No information avaliable

Arvynol Chemical_Formula


Arvynol RX_link

Arvynol fda sheet

Arvynol FDA

Arvynol msds (material safety sheet)

Arvynol MSDS

Arvynol Synthesis Reference

No information avaliable

Arvynol Molecular Weight

206.028 g/mol

Arvynol Melting Point

No information avaliable

Arvynol H2O Solubility

No information avaliable

Arvynol State


Arvynol LogP


Arvynol Dosage Forms

Solution for injection (50mg/mL); Tablet (200, 400 mg)

Arvynol Indication

For the treatment of symptomatic Paget's disease of bone and in the prevention and treatment of heterotopic ossification following total hip replacement or due to spinal cord injury.

Arvynol Pharmacology

Etidronate is a first generation (non-nitrogenous) bisphosphonate in the same family as clodronate and tiludronate. Etidronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the etidronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Etidronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Arvynol Absorption

The amount of drug absorbed after an oral dose is approximately 3%.

Arvynol side effects and Toxicity

Clinical experience with acute etidronate overdosage is extremely limited. Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients. Some patients may develop vomiting. In one event, an 18-year-old female who ingested an estimated single dose of 4800 to 6000 mg (67 to 100 mg/kg) of etidronate was reported to be mildly hypocalcemic (7 .5 2 mg/ dl) and experienced paresthesia of the fingers.

Arvynol Patient Information

Arvynol Organisms Affected

Humans and other mammals