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Normonson Brand names, Normonson Analogs

Normonson Brand Names Mixture

  • No information avaliable

Normonson Chemical_Formula


Normonson RX_link

Normonson fda sheet

Normonson FDA

Normonson msds (material safety sheet)

Normonson MSDS

Normonson Synthesis Reference

No information avaliable

Normonson Molecular Weight

206.028 g/mol

Normonson Melting Point

No information avaliable

Normonson H2O Solubility

No information avaliable

Normonson State


Normonson LogP


Normonson Dosage Forms

Solution for injection (50mg/mL); Tablet (200, 400 mg)

Normonson Indication

For the treatment of symptomatic Paget's disease of bone and in the prevention and treatment of heterotopic ossification following total hip replacement or due to spinal cord injury.

Normonson Pharmacology

Etidronate is a first generation (non-nitrogenous) bisphosphonate in the same family as clodronate and tiludronate. Etidronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the etidronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Etidronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Normonson Absorption

The amount of drug absorbed after an oral dose is approximately 3%.

Normonson side effects and Toxicity

Clinical experience with acute etidronate overdosage is extremely limited. Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients. Some patients may develop vomiting. In one event, an 18-year-old female who ingested an estimated single dose of 4800 to 6000 mg (67 to 100 mg/kg) of etidronate was reported to be mildly hypocalcemic (7 .5 2 mg/ dl) and experienced paresthesia of the fingers.

Normonson Patient Information

Normonson Organisms Affected

Humans and other mammals