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Myproic Acid Brand names, Myproic Acid Analogs

Myproic Acid Brand Names Mixture

  • No information avaliable

Myproic Acid Chemical_Formula


Myproic Acid RX_link

Myproic Acid fda sheet

Myproic Acid msds (material safety sheet)

Myproic_Acid MSDS

Myproic Acid Synthesis Reference

Oberreit, Ber.29, 1998 (1896)

Myproic Acid Molecular Weight

144.211 g/mol

Myproic Acid Melting Point

120 - 130 oC

Myproic Acid H2O Solubility

Slightly soluble (1.3 mg/mL)

Myproic Acid State


Myproic Acid LogP


Myproic Acid Dosage Forms

Capsule (250 mg); Syrup (250 mg drug/5mL syrup)

Myproic Acid Indication

For use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types which include absence seizures.

Myproic Acid Pharmacology

Valproic Acid is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder. It is also used to treat migraine headaches and schizophrenia. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome. Valproic Acid is believed to affect the function of the neurotransmitter GABA (as a GABA transaminase inhibitor) in the human brain. Valproic Acid dissociates to the valproate ion in the gastrointestinal tract. Valproic acid has also been shown to be an inhibitor of an enzyme called histone deacetylase 1 (HDAC1). HDAC1 is needed for HIV to remain in infected cells. A study published in August 2005 revealed that patients treated with valproic acid in addition to highly active antiretroviral therapy (HAART) showed a 75% reduction in latent HIV infection.

Myproic Acid Absorption

Rapid absorption from gastrointestinal tract.

Myproic Acid side effects and Toxicity

Oral, mouse: LD50 = 1098 mg/kg; Oral, rat: LD50 = 670 mg/kg. Symptoms of overdose may include coma, extreme drowsiness, and heart problems.

Myproic Acid Patient Information

Since valproate products may produce CNS depression, especially when combined with another CNS depressant (eg, alcohol), patients should be advised not to engage in hazardous activities, such as driving an automobile or operating dangerous machinery, until it is known that they do not become drowsy from the drug.

Myproic Acid Organisms Affected

Humans and other mammals