Myobloc (Elan Corp
Brand names,
Myobloc (Elan Corp
Analogs
Myobloc (Elan Corp
Brand Names Mixture
Myobloc (Elan Corp
Chemical_Formula
C6760H10447N1743O2010S32
Myobloc (Elan Corp
RX_link
http://www.rxlist.com/cgi/generic2/botulinumtoxin.htm
Myobloc (Elan Corp
fda sheet
Myobloc (Elan Corp
msds (material safety sheet)
Myobloc (Elan Corp
Synthesis Reference
No information avaliable
Myobloc (Elan Corp
Molecular Weight
149322.7
Myobloc (Elan Corp
Melting Point
No information avaliable
Myobloc (Elan Corp
H2O Solubility
No information avaliable
Myobloc (Elan Corp
State
Liquid
Myobloc (Elan Corp
LogP
-0.368
Myobloc (Elan Corp
Dosage Forms
Solution
Myobloc (Elan Corp
Indication
For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles
Myobloc (Elan Corp
Pharmacology
Myobloc inhibits acetylcholine release at the neuromuscular junction via a three stage process: 1) Heavy Chain mediated neurospecific binding of the toxin, 2) internalization of the toxin by receptor-mediated endocytosis, and 3) ATP and pH dependent translocation of the Light Chain to the neuronal cytosol where it acts as a zinc-dependent endoprotease cleaving polypeptides essential for neurotransmitter release.
Myobloc (Elan Corp
Absorption
No information avaliable
Myobloc (Elan Corp
side effects and Toxicity
No information avaliable
Myobloc (Elan Corp
Patient Information
No information avaliable
Myobloc (Elan Corp
Organisms Affected
Humans and other mammals