Bontoxilysin A
Brand names,
Bontoxilysin A
Analogs
Bontoxilysin A
Brand Names Mixture
Bontoxilysin A
Chemical_Formula
C6760H10447N1743O2010S32
Bontoxilysin A
RX_link
http://www.rxlist.com/cgi/generic2/botulinumtoxin.htm
Bontoxilysin A
fda sheet
Bontoxilysin A
msds (material safety sheet)
Bontoxilysin A
Synthesis Reference
No information avaliable
Bontoxilysin A
Molecular Weight
149322.7
Bontoxilysin A
Melting Point
No information avaliable
Bontoxilysin A
H2O Solubility
No information avaliable
Bontoxilysin A
State
Liquid
Bontoxilysin A
LogP
-0.368
Bontoxilysin A
Dosage Forms
Solution
Bontoxilysin A
Indication
For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles
Bontoxilysin A
Pharmacology
Myobloc inhibits acetylcholine release at the neuromuscular junction via a three stage process: 1) Heavy Chain mediated neurospecific binding of the toxin, 2) internalization of the toxin by receptor-mediated endocytosis, and 3) ATP and pH dependent translocation of the Light Chain to the neuronal cytosol where it acts as a zinc-dependent endoprotease cleaving polypeptides essential for neurotransmitter release.
Bontoxilysin A
Absorption
No information avaliable
Bontoxilysin A
side effects and Toxicity
No information avaliable
Bontoxilysin A
Patient Information
No information avaliable
Bontoxilysin A
Organisms Affected
Humans and other mammals