Botulinum neurotoxin type A precursor
Brand names,
Botulinum neurotoxin type A precursor
Analogs
Botulinum neurotoxin type A precursor
Brand Names Mixture
Botulinum neurotoxin type A precursor
Chemical_Formula
C6760H10447N1743O2010S32
Botulinum neurotoxin type A precursor
RX_link
http://www.rxlist.com/cgi/generic2/botulinumtoxin.htm
Botulinum neurotoxin type A precursor
fda sheet
Botulinum neurotoxin type A precursor
msds (material safety sheet)
Botulinum neurotoxin type A precursor
Synthesis Reference
No information avaliable
Botulinum neurotoxin type A precursor
Molecular Weight
149322.7
Botulinum neurotoxin type A precursor
Melting Point
No information avaliable
Botulinum neurotoxin type A precursor
H2O Solubility
No information avaliable
Botulinum neurotoxin type A precursor
State
Liquid
Botulinum neurotoxin type A precursor
LogP
-0.368
Botulinum neurotoxin type A precursor
Dosage Forms
Solution
Botulinum neurotoxin type A precursor
Indication
For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles
Botulinum neurotoxin type A precursor
Pharmacology
Myobloc inhibits acetylcholine release at the neuromuscular junction via a three stage process: 1) Heavy Chain mediated neurospecific binding of the toxin, 2) internalization of the toxin by receptor-mediated endocytosis, and 3) ATP and pH dependent translocation of the Light Chain to the neuronal cytosol where it acts as a zinc-dependent endoprotease cleaving polypeptides essential for neurotransmitter release.
Botulinum neurotoxin type A precursor
Absorption
No information avaliable
Botulinum neurotoxin type A precursor
side effects and Toxicity
No information avaliable
Botulinum neurotoxin type A precursor
Patient Information
No information avaliable
Botulinum neurotoxin type A precursor
Organisms Affected
Humans and other mammals