Mexiletine HCL en es it fr

Mexiletine HCL Brand names, Mexiletine HCL Analogs

Mexiletine HCL Brand Names Mixture

  • No information avaliable

Mexiletine HCL Chemical_Formula


Mexiletine HCL RX_link

Mexiletine HCL fda sheet

Mexiletine_HCL FDA

Mexiletine HCL msds (material safety sheet)

Mexiletine_HCL MSDS

Mexiletine HCL Synthesis Reference

No information avaliable

Mexiletine HCL Molecular Weight

179.259 g/mol

Mexiletine HCL Melting Point

203-205 oC

Mexiletine HCL H2O Solubility

8.25 mg/mL

Mexiletine HCL State


Mexiletine HCL LogP


Mexiletine HCL Dosage Forms

Capsule (150 mg, 200 mg and 250 mg)

Mexiletine HCL Indication

For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.

Mexiletine HCL Pharmacology

Mexiletine is a local anesthetic, antiarrhythmic agent (Class Ib), structurally similar to lidocaine, but orally active. Mexiletine has fast onset and offset kinetics, meaning that they have little or no effect at slower heart rates, and more effects at faster heart rates. It shortens the action potential duration, reduces refractoriness, and decreases Vmax in partially depolarized cells with fast response action potentials. Mexiletine either does not change the action potential duration, or decreases the action potential duration.

Mexiletine HCL Absorption

Well absorbed (bioavailability 90%) from the gastrointenstinal tract.

Mexiletine HCL side effects and Toxicity

Symptoms of overdose include nausea, hypotension, sinus bradycardia, paresthesia, seizures, bundle branch block, AV heart block, asystole, ventricular tachyarrythmia, including ventricular fibrillation, cardiovascular collapse, and coma.

Mexiletine HCL Patient Information

No information avaliable

Mexiletine HCL Organisms Affected

Humans and other mammals