Mexiletina [INN-Spanish] en es it fr

Mexiletina [INN-Spanish] Brand names, Mexiletina [INN-Spanish] Analogs

Mexiletina [INN-Spanish] Brand Names Mixture

  • No information avaliable

Mexiletina [INN-Spanish] Chemical_Formula


Mexiletina [INN-Spanish] RX_link

Mexiletina [INN-Spanish] fda sheet

Mexiletina_[INN-Spanish] FDA

Mexiletina [INN-Spanish] msds (material safety sheet)

Mexiletina_[INN-Spanish] MSDS

Mexiletina [INN-Spanish] Synthesis Reference

No information avaliable

Mexiletina [INN-Spanish] Molecular Weight

179.259 g/mol

Mexiletina [INN-Spanish] Melting Point

203-205 oC

Mexiletina [INN-Spanish] H2O Solubility

8.25 mg/mL

Mexiletina [INN-Spanish] State


Mexiletina [INN-Spanish] LogP


Mexiletina [INN-Spanish] Dosage Forms

Capsule (150 mg, 200 mg and 250 mg)

Mexiletina [INN-Spanish] Indication

For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.

Mexiletina [INN-Spanish] Pharmacology

Mexiletine is a local anesthetic, antiarrhythmic agent (Class Ib), structurally similar to lidocaine, but orally active. Mexiletine has fast onset and offset kinetics, meaning that they have little or no effect at slower heart rates, and more effects at faster heart rates. It shortens the action potential duration, reduces refractoriness, and decreases Vmax in partially depolarized cells with fast response action potentials. Mexiletine either does not change the action potential duration, or decreases the action potential duration.

Mexiletina [INN-Spanish] Absorption

Well absorbed (bioavailability 90%) from the gastrointenstinal tract.

Mexiletina [INN-Spanish] side effects and Toxicity

Symptoms of overdose include nausea, hypotension, sinus bradycardia, paresthesia, seizures, bundle branch block, AV heart block, asystole, ventricular tachyarrythmia, including ventricular fibrillation, cardiovascular collapse, and coma.

Mexiletina [INN-Spanish] Patient Information

No information avaliable

Mexiletina [INN-Spanish] Organisms Affected

Humans and other mammals