Metipranololum [Inn-Latin]
Brand names,
Metipranololum [Inn-Latin]
Analogs
Metipranololum [Inn-Latin]
Brand Names Mixture
Metipranololum [Inn-Latin]
Chemical_Formula
C17H27NO4
Metipranololum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/optipran.htm
Metipranololum [Inn-Latin]
fda sheet
Metipranololum [Inn-Latin]
msds (material safety sheet)
Metipranololum [Inn-Latin]
Synthesis Reference
No information avaliable
Metipranololum [Inn-Latin]
Molecular Weight
309.401 g/mol
Metipranololum [Inn-Latin]
Melting Point
105-107 oC
Metipranololum [Inn-Latin]
H2O Solubility
589 mg/L
Metipranololum [Inn-Latin]
State
Solid
Metipranololum [Inn-Latin]
LogP
3.034
Metipranololum [Inn-Latin]
Dosage Forms
No information avaliable
Metipranololum [Inn-Latin]
Indication
Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma.
Metipranololum [Inn-Latin]
Pharmacology
Metipranolol is a beta1 and beta2 (non-selective) adrenergic receptor-blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Metipranolol is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metipranolol, when applied topically to the eye, has the action of reducing elevated, as well as normal, intraocular pressure, whether or not accompanied by glaucoma. Elevated intraocular pressure is a major risk factor in the pathogenesis of glaucomatous visual field loss and optic nerve damage. Metipranolol reduces intraocular pressure with little or no effect on pupil size or accommodation in contrast to the miosis which cholinergic agents are known to produce.
Metipranololum [Inn-Latin]
Absorption
No information avaliable
Metipranololum [Inn-Latin]
side effects and Toxicity
No information avaliable
Metipranololum [Inn-Latin]
Patient Information
Metipranololum [Inn-Latin]
Organisms Affected
Humans and other mammals