METIPRANOLOL HYDROCHLORIDE
Brand names,
METIPRANOLOL HYDROCHLORIDE
Analogs
METIPRANOLOL HYDROCHLORIDE
Brand Names Mixture
METIPRANOLOL HYDROCHLORIDE
Chemical_Formula
C17H27NO4
METIPRANOLOL HYDROCHLORIDE
RX_link
http://www.rxlist.com/cgi/generic3/optipran.htm
METIPRANOLOL HYDROCHLORIDE
fda sheet
METIPRANOLOL HYDROCHLORIDE
msds (material safety sheet)
METIPRANOLOL HYDROCHLORIDE
Synthesis Reference
No information avaliable
METIPRANOLOL HYDROCHLORIDE
Molecular Weight
309.401 g/mol
METIPRANOLOL HYDROCHLORIDE
Melting Point
105-107 oC
METIPRANOLOL HYDROCHLORIDE
H2O Solubility
589 mg/L
METIPRANOLOL HYDROCHLORIDE
State
Solid
METIPRANOLOL HYDROCHLORIDE
LogP
3.034
METIPRANOLOL HYDROCHLORIDE
Dosage Forms
No information avaliable
METIPRANOLOL HYDROCHLORIDE
Indication
Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma.
METIPRANOLOL HYDROCHLORIDE
Pharmacology
Metipranolol is a beta1 and beta2 (non-selective) adrenergic receptor-blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Metipranolol is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metipranolol, when applied topically to the eye, has the action of reducing elevated, as well as normal, intraocular pressure, whether or not accompanied by glaucoma. Elevated intraocular pressure is a major risk factor in the pathogenesis of glaucomatous visual field loss and optic nerve damage. Metipranolol reduces intraocular pressure with little or no effect on pupil size or accommodation in contrast to the miosis which cholinergic agents are known to produce.
METIPRANOLOL HYDROCHLORIDE
Absorption
No information avaliable
METIPRANOLOL HYDROCHLORIDE
side effects and Toxicity
No information avaliable
METIPRANOLOL HYDROCHLORIDE
Patient Information
METIPRANOLOL HYDROCHLORIDE
Organisms Affected
Humans and other mammals