Disorat
Disorat Brand names, Disorat Analogs
Disorat Brand Names Mixture
- No information avaliable
Disorat Chemical_Formula
C17H27NO4
Disorat RX_link
http://www.rxlist.com/cgi/generic3/optipran.htm
Disorat fda sheet
Disorat msds (material safety sheet)
Disorat Synthesis Reference
No information avaliable
Disorat Molecular Weight
309.401 g/mol
Disorat Melting Point
105-107 oC
Disorat H2O Solubility
589 mg/L
Disorat State
Solid
Disorat LogP
3.034
Disorat Dosage Forms
No information avaliable
Disorat Indication
Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma.
Disorat Pharmacology
Metipranolol is a beta1 and beta2 (non-selective) adrenergic receptor-blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Metipranolol is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metipranolol, when applied topically to the eye, has the action of reducing elevated, as well as normal, intraocular pressure, whether or not accompanied by glaucoma. Elevated intraocular pressure is a major risk factor in the pathogenesis of glaucomatous visual field loss and optic nerve damage. Metipranolol reduces intraocular pressure with little or no effect on pupil size or accommodation in contrast to the miosis which cholinergic agents are known to produce.
Disorat Absorption
No information avaliable
Disorat side effects and Toxicity
No information avaliable
Disorat Patient Information
Disorat Organisms Affected
Humans and other mammals
