Methoxsalen
Brand names,
Methoxsalen
Analogs
Methoxsalen
Brand Names Mixture
Methoxsalen
Chemical_Formula
C12H8O4
Methoxsalen
RX_link
http://www.rxlist.com/cgi/generic2/methox.htm
Methoxsalen
fda sheet
Methoxsalen
msds (material safety sheet)
Methoxsalen
Synthesis Reference
No information avaliable
Methoxsalen
Molecular Weight
216.19 g/mol
Methoxsalen
Melting Point
No information avaliable
Methoxsalen
H2O Solubility
No information avaliable
Methoxsalen
State
Solid
Methoxsalen
LogP
2.336
Methoxsalen
Dosage Forms
Liquid
Methoxsalen
Indication
For the treatment of psoriasis and vitiligo
Methoxsalen
Pharmacology
Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.
Methoxsalen
Absorption
No information avaliable
Methoxsalen
side effects and Toxicity
No information avaliable
Methoxsalen
Patient Information
Patients should be told emphatically to wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a
sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen, whether exposed
to direct or indirect sunlight in the open or through a window glass.
Methoxsalen
Organisms Affected
Humans and other mammals