Meladinine
Brand names,
Meladinine
Analogs
Meladinine
Brand Names Mixture
Meladinine
Chemical_Formula
C12H8O4
Meladinine
RX_link
http://www.rxlist.com/cgi/generic2/methox.htm
Meladinine
fda sheet
Meladinine
msds (material safety sheet)
Meladinine
Synthesis Reference
No information avaliable
Meladinine
Molecular Weight
216.19 g/mol
Meladinine
Melting Point
No information avaliable
Meladinine
H2O Solubility
No information avaliable
Meladinine
State
Solid
Meladinine
LogP
2.336
Meladinine
Dosage Forms
Liquid
Meladinine
Indication
For the treatment of psoriasis and vitiligo
Meladinine
Pharmacology
Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.
Meladinine
Absorption
No information avaliable
Meladinine
side effects and Toxicity
No information avaliable
Meladinine
Patient Information
Patients should be told emphatically to wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a
sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen, whether exposed
to direct or indirect sunlight in the open or through a window glass.
Meladinine
Organisms Affected
Humans and other mammals