Puvalen
Brand names,
Puvalen
Analogs
Puvalen
Brand Names Mixture
Puvalen
Chemical_Formula
C12H8O4
Puvalen
RX_link
http://www.rxlist.com/cgi/generic2/methox.htm
Puvalen
fda sheet
Puvalen
msds (material safety sheet)
Puvalen
Synthesis Reference
No information avaliable
Puvalen
Molecular Weight
216.19 g/mol
Puvalen
Melting Point
No information avaliable
Puvalen
H2O Solubility
No information avaliable
Puvalen
State
Solid
Puvalen
LogP
2.336
Puvalen
Dosage Forms
Liquid
Puvalen
Indication
For the treatment of psoriasis and vitiligo
Puvalen
Pharmacology
Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.
Puvalen
Absorption
No information avaliable
Puvalen
side effects and Toxicity
No information avaliable
Puvalen
Patient Information
Patients should be told emphatically to wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a
sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen, whether exposed
to direct or indirect sunlight in the open or through a window glass.
Puvalen
Organisms Affected
Humans and other mammals