Methoxalen
Brand names,
Methoxalen
Analogs
Methoxalen
Brand Names Mixture
Methoxalen
Chemical_Formula
C12H8O4
Methoxalen
RX_link
http://www.rxlist.com/cgi/generic2/methox.htm
Methoxalen
fda sheet
Methoxalen
msds (material safety sheet)
Methoxalen
Synthesis Reference
No information avaliable
Methoxalen
Molecular Weight
216.19 g/mol
Methoxalen
Melting Point
No information avaliable
Methoxalen
H2O Solubility
No information avaliable
Methoxalen
State
Solid
Methoxalen
LogP
2.336
Methoxalen
Dosage Forms
Liquid
Methoxalen
Indication
For the treatment of psoriasis and vitiligo
Methoxalen
Pharmacology
Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.
Methoxalen
Absorption
No information avaliable
Methoxalen
side effects and Toxicity
No information avaliable
Methoxalen
Patient Information
Patients should be told emphatically to wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a
sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen, whether exposed
to direct or indirect sunlight in the open or through a window glass.
Methoxalen
Organisms Affected
Humans and other mammals