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Mepivacaine en es it fr

Mepivacaine Brand names, Mepivacaine Analogs

Mepivacaine Brand Names Mixture

  • For sope (sodium lauryl sulfate + stearic acid)
  • Plax anti-plaque den rinse peppermint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
  • Plax anti-plaque dent rinse soft mint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
  • Plax anti-plaque dental rinse (sodium benzoate + sodium lauryl sulfate + sodium salicylate)

Mepivacaine Chemical_Formula

C15H22N2O

Mepivacaine RX_link

http://www.rxlist.com/cgi/generic2/mepivacaine.htm

Mepivacaine fda sheet

Mepivacaine msds (material safety sheet)

Mepivacaine MSDS

Mepivacaine Synthesis Reference

No information avaliable

Mepivacaine Molecular Weight

246.348 g/mol

Mepivacaine Melting Point

150.5 oC

Mepivacaine H2O Solubility

Soluble (7000 mg/L)

Mepivacaine State

Solid

Mepivacaine LogP

2.674

Mepivacaine Dosage Forms

Liquid; Solution

Mepivacaine Indication

For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.

Mepivacaine Pharmacology

Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.

Mepivacaine Absorption

Absorbed locally. The rate of systemic absorption of local anesthetics is dependent upon the total dose and concentration of drug administered, the route of administration, the vascularity of the administration site, and the presence or absence of epinephrine in the anesthetic solution.

Mepivacaine side effects and Toxicity

The mean seizure dosage of mepivacaine in rhesus monkeys was found to be 18.8 mg/kg with mean arterial plasma concentration of 24.4 µg/mL. The intravenous and subcutaneous LD 50 in mice is 23 mg/kg to 35 mg/kg and 280 mg/kg respectively.

Mepivacaine Patient Information

Mepivacaine Organisms Affected

Humans and other mammals