Mazindolum [INN-Latin] en es it fr

Mazindolum [INN-Latin] Brand names, Mazindolum [INN-Latin] Analogs

Mazindolum [INN-Latin] Brand Names Mixture

  • For sope (sodium lauryl sulfate + stearic acid)
  • Plax anti-plaque den rinse peppermint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
  • Plax anti-plaque dent rinse soft mint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
  • Plax anti-plaque dental rinse (sodium benzoate + sodium lauryl sulfate + sodium salicylate)

Mazindolum [INN-Latin] Chemical_Formula

C15H22N2O

Mazindolum [INN-Latin] RX_link

http://www.rxlist.com/cgi/generic2/mepivacaine.htm

Mazindolum [INN-Latin] fda sheet

Mazindolum [INN-Latin] msds (material safety sheet)

Mazindolum_[INN-Latin] MSDS

Mazindolum [INN-Latin] Synthesis Reference

No information avaliable

Mazindolum [INN-Latin] Molecular Weight

246.348 g/mol

Mazindolum [INN-Latin] Melting Point

150.5 oC

Mazindolum [INN-Latin] H2O Solubility

Soluble (7000 mg/L)

Mazindolum [INN-Latin] State

Solid

Mazindolum [INN-Latin] LogP

2.674

Mazindolum [INN-Latin] Dosage Forms

Liquid; Solution

Mazindolum [INN-Latin] Indication

For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.

Mazindolum [INN-Latin] Pharmacology

Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.

Mazindolum [INN-Latin] Absorption

Absorbed locally. The rate of systemic absorption of local anesthetics is dependent upon the total dose and concentration of drug administered, the route of administration, the vascularity of the administration site, and the presence or absence of epinephrine in the anesthetic solution.

Mazindolum [INN-Latin] side effects and Toxicity

The mean seizure dosage of mepivacaine in rhesus monkeys was found to be 18.8 mg/kg with mean arterial plasma concentration of 24.4 µg/mL. The intravenous and subcutaneous LD 50 in mice is 23 mg/kg to 35 mg/kg and 280 mg/kg respectively.

Mazindolum [INN-Latin] Patient Information

Mazindolum [INN-Latin] Organisms Affected

Humans and other mammals